Parkinson's disease (PD) is a chronic neurodegenerative movement disorder affecting the (extrapyramidal) motor system, characteristically manifesting as bradykinesia, rigidity, tremor and postural ...
CADASIL is a rare mid-adult onset monogenic form of hereditary cerebral microangiopathy, caused by mutations in the NOTCH3 gene which lead to abnormal extracellular matrix accumulation of granular ...