The acute respiratory distress syndrome (ARDS) is a complex disorder associated with rapidly progressive lung inflammation, non-cardiogenic pulmonary edema, hypoxemic respiratory failure and one or...
Adolescent brain development is a fascinating, newly developing field that has so much to offer almost anyone interested in learning more. Adolescence has only come to be established as a unique de...
This book offers a comprehensive overview of Alexander disease, a rare and devastating neurological disorder that often affects the white matter of the brain and spinal cord.
Its distinct...
Multi-cellular organisms eliminate individual cells through a self-destruct process known as apoptosis. Apoptosis is critical for proper development and maintenance of tissue homeostasis. The impor...
This volume deals with the history, aetiology, pathophysiology, symptoms, signs, prognosis, and rational treatment of ascites. During the past decade, our knowledge of the pathophysiology of ascite...
Exercise is the act of increasing metabolic rate for the purpose of enhancing physical fitness. Exercise can be one of the most stressful physiological responses that the body undertakes. With exer...
The major purpose of this book is to review the evidence supporting the concept that intrinsic cell survival programs can be activated by a variety of mildly noxious stimuli or pharmacologic agents...
Several physiological mechanisms act to regulate renal potassium excretion and distribution. Together they comprise an integrated control system that may be envisioned as being made up of several i...
Numerous epidemiological studies report that birth weight is inversely associated with blood pressure, suggesting that slow growth during fetal life programs hypertension and increased risk for car...
The understanding of the pathophysiology of erectile dysfunction (ED) has advanced significantly over the past two decades. In this ebook, we provide an in-depth analysis of the current knowledge o...
In the vast majority of patients, hypertension has no identifiable cause. Moreover, despite decades of discovery and therapeutic development, approximately only half of the hypertensive patients ar...
Food and water are necessary for survival, but can only be obtained via ingestive behavior (feeding, drinking, and moving). Survival thus depends on the ability of the brain to coordinate the need ...
This ebook describes the pathogenesis of malaria and the major consequences of the parasitism to the vertebrate host. Malaria is one of the oldest infectious diseases of mankind, which still exerts...
Alzheimer's Disease is characterized pathologically by two principal hallmark lesions: the senile plaque and the neurofibrillary tangle. Since the identification of each over 100 years ago, the maj...
Classically, the central nervous system (CNS) was considered to contain neurons and three main types of glial cells-astrocytes, oligodendrocytes, and microglia. Now, it has been clearly established...
The circulatory system provides the tissues of the body with oxygen and nutrients for survival, allows for the dissemination of inflammatory cells, and clears metabolic waste from building up and d...
Pulmonary hypertension is a life-threatening disease with no known cure. Here we provide a concise yet comprehensive review of the current knowledge about the pathophysiology of pulmonary hypertens...
Peripheral arterial disease (PAD) is a cardiovascular disorder of the peripheral vasculature due to progressive atherosclerotic stenosis of conduit arteries restricting blood flow to tissues. PAD i...
The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the b...
The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, ...